<em>PADUA</em>

The seat carries out research and technology transfer in different areas of chemistry, materials and energetics

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PADUA PADUA
Headquarter

<em>MILAN</em>

Research activity in Milan concerns the properties and technology of structural and functional materials, fluid dynamics, and diagnostics or reactive systems.

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MILAN MILAN
Organizative Unit

<em>GENOA</em>

ICMATE-Genoa has expertise in the fields of physical chemistry of interfaces and in the preparation of powders, ceramics and composites of functional oxides.

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GENOA GENOA
Organizative Unit

<em>LECCO</em>

ICMATE-Lecco is one of the few centers in Italy able to operate in the secondary metallurgy of advanced metallic materials

VISIT

LECCO LECCO
Organizative Unit

Metals in medicine applications
  • Synthesis and biological evaluation of metallic compounds of Technetium-99m and Rhenium-188 for theranostic applications in Nuclear Medicine
    Radiopharmaceuticals (RP) are drugs containing radioactive isotopes of certain elements, used in nuclear medicine for diagnosis and/or therapy. The systemic administration of 'target' specific RPs, which provides a specific distribution of the radionuclide to tumor sites is an interesting opportunity for the diagnosis and the therapy of tumors/metastases. The development of a 'target-specific' RP is conditioned by the availability of appropriate radionuclides, efficient labelling procedures that leaves unaltered the biological property of the native molecule and reliable targeting vector.
  • Copper (I) complexes as potential anticancer agents
    Since the discovery of the antitumor activity of cisplatin cis-[PtCl2(NH3)2] for the treatment of several human tumors, thousands of platinum and other metal–based compounds have been tested for their potential antitumor properties in the last 40 years. Aim of this search is to overcome the drawbacks of Pt(II) derivatives such low specificity, high toxicity and inherited and/or acquired drug resistance.

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Radiochemical approach to environmental investigation
  1. Study of environmental phenomena through radiochemical approach
  2. Studies of natural and artificial radionuclides mobility in the environment for their potential danger for man health or environment
  3. Development of radioanalytical methodologies and monitoring technologies

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  • Synthesis and biological evaluation of metallic compounds of Technetium-99m and Rhenium-188 for theranostic applications in Nuclear Medicine
    Radiopharmaceuticals (RP) are drugs containing radioactive isotopes of certain elements, used in nuclear medicine for diagnosis and/or therapy. The systemic administration of 'target' specific RPs, which provides a specific distribution of the radionuclide to tumor sites is an interesting opportunity for the diagnosis and the therapy of tumors/metastases. The development of a 'target-specific' RP is conditioned by the availability of appropriate radionuclides, efficient labelling procedures that leaves unaltered the biological property of the native molecule and reliable targeting vector.
  • Copper (I) complexes as potential anticancer agents
    Since the discovery of the antitumor activity of cisplatin cis-[PtCl2(NH3)2] for the treatment of several human tumors, thousands of platinum and other metal–based compounds have been tested for their potential antitumor properties in the last 40 years. Aim of this search is to overcome the drawbacks of Pt(II) derivatives such low specificity, high toxicity and inherited and/or acquired drug resistance.

  1. Study of environmental phenomena through radiochemical approach
  2. Studies of natural and artificial radionuclides mobility in the environment for their potential danger for man health or environment
  3. Development of radioanalytical methodologies and monitoring technologies